SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in periodicals archive ?
Although both sides--for and against primogeniture--used the Genesis narrative to support their views, its portrayal of sonship actually favors the younger over the elder son.
Although the fall of humankind generated confusion and division, there is, as Archbishop Gregory Afonsky expressed it, a "divine plan to conform fallen mankind to sonship in Christ through the Holy Spirit.
He finds the foundations for central elements of subsequent orthodoxy in the speculative theology of the second century--apophatic theology in the Apocryphon of John; humanity as the divine image in the teachings of Valentinus; the eternal sonship of the savior in Basilides; and beginnings of theological anthropology in Marcion, raising the question of which of the "creeds" of Irenaeus or Valentinus and the Gnostics would most approximate the later "catholic" norm.
This portrayal of Fanny Dashwood's persuasive role, however, also emphasizes another important aspect of sonship: that the woman he chooses to marry will enhance or impede his progress from sonship to mature manhood.
The father delights in his return, restores his sonship, and declares a banquet.
Here the eternally begotten Son of God became man, and so made it possible for us, his brothers and sisters, to share in His divine sonship.
The many studies of sonship in Judaism and of Jewish mysticism have barely, if at all, acknowledged one another, so Idel believes his is the first attempt to investigate the intersection between them as a focused topic.
The divine sonship of Jesus is explicitly announced already in 2:15.
As a Protestant steeped in covenant theology, Hahn found the concept of sonship enormously attractive and uses it to explain how this "divinization" can sanctify everything that fills up a human life, including work and the family.
25) Themes include divine sonship and chosen heir of the deity (SAA 9 1.
Jones & Company and West Bay SonShip Yachts turned to Avatech for SMARTEAM PLM solutions to help them improve their business processes, reduce costs, fuel innovation and shorten time-to-market.