SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in classic literature ?
The sons of Aeacus who rejoiced in battle as though a feast.
83: Some write `Serus the son of Halirrhothius', whom Hesiod mentions: `He (begot) Serus and Alazygus, goodly sons.
16-19) And the two sons of Amphiaraus the lord, Oecleus' son, sought her to wife from Argos very near at hand; yet.
but there was no deceitful dealing in the sons of Tyndareus.
With this the son of Peleus dashed his gold-bestudded sceptre on the ground and took his seat, while the son of Atreus was beginning fiercely from his place upon the other side.
The son of Peleus went back to his tents and ships with the son of Menoetius and his company, while Agamemnon drew a vessel into the water and chose a crew of twenty oarsmen.
But the son of Atreus bade the people purify themselves; so they purified themselves and cast their filth into the sea.
Go," said he, "to the tent of Achilles, son of Peleus; take Briseis by the hand and bring her hither; if he will not give her I shall come with others and take her--which will press him harder.
They gathered round the ghost of the son of Peleus, and the ghost of Agamemnon joined them, sorrowing bitterly.
Better for you had you fallen at Troy in the hey-day of your renown, for the Achaeans would have built a mound over your ashes, and your son would have been heir to your good name, whereas it has now been your lot to come to a most miserable end.
The ghost of Agamemnon recognised Amphimedon son of Melaneus, who lived in Ithaca and had been his host, so it began to talk to him.
Since then my son has become a widower and has gone travelling.