Somogyi effect

So·mo·gyi effect (sm-j)

n.

In diabetes, the occurrence of reactive hyperglycemia following hypoglycemia. Also called posthypoglycemic hyperglycemia, Somogyi phenomenon.

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Somogyi effect

a rebound phenomenon occurring in diabetes mellitus; overtreatment with insulin induces hypoglycemia, which initiates the release of epinephrine, ACTH, glucagon and growth hormone, which stimulate lipolysis, gluconeogenesis and glycogenolysis, which, in turn, result in rebound hyperglycemia and ketosis.