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soft tissue sarcoma
(redirected from Soft-tissue sarcoma)

   Also found in: Wikipedia 0.01 sec.
sarcoma /sar·co·ma/ (sahr-ko´mah) pl. sarcomas, sarco´mata   any of a group of tumors usually arising from connective tissue, although the term now includes some of epithelial origin; most are malignant.
alveolar soft part sarcoma  a well-circumscribed, painless, highly metastatic neoplasm with a distinctive alveolar pattern, usually in the limbs, head, and neck of young adults.
ameloblastic sarcoma  see under fibrosarcoma.
botryoid sarcoma , sarcoma botryoi´des an embryonal rhabdomyosarcoma arising in submucosal tissue, usually in the upper vagina, cervix uteri, or neck of urinary bladder in young children and infants, presenting grossly as a polypoid grapelike structure.
clear cell sarcoma of kidney  a malignant kidney tumor similar to Wilms' tumor but with poorer prognosis, often metastasizing to bone.
endometrial stromal sarcoma  a pale, polypoid, fleshy, malignant tumor of the endometrial stroma.
Ewing's sarcoma  a highly malignant, metastatic, primitive small round cell tumor of bone, usually in the diaphyses of long bones, ribs, and flat bones of children and adolescents.
giant cell sarcoma 
1. a form of giant cell tumor of bone arising malignant de novo rather than transforming to malignancy.
2. sarcoma characterized by large anaplastic (giant) cells.
hemangioendothelial sarcoma  hemangiosarcoma.
immunoblastic sarcoma of B cells  large cell immunoblastic lymphoma composed predominantly of B cells.
immunoblastic sarcoma of T cells  large cell immunoblastic lymphoma composed predominantly of T cells.
Kaposi sarcoma  a multicentric, malignant neoplastic vascular proliferation, characterized by the development of bluish-red nodules on the skin, sometimes with widespread visceral involvement; a particularly virulent, disseminated form occurs in immunocompromised patients.
Kupffer cell sarcoma  hepatic angiosarcoma.
osteogenic sarcoma  osteosarcoma.
pseudo–Kaposi sarcoma  unilateral subacute to chronic dermatitis occurring in association with an underlying arteriovenous fistula and closely resembling Kaposi's sarcoma clinically and histologically.
reticulum cell sarcoma  histiocytic lymphoma.
Rous sarcoma  a virus-induced sarcoma-like growth of fowls.
soft tissue sarcoma  a general term for a malignant tumor derived from extraskeletal connective tissue, including fibrous, fat, smooth muscle, nerve, vascular, histiocytic, and synovial tissue, with almost all lesions arising from primitive mesoderm.
spindle cell sarcoma 
1. any sarcoma composed of spindle-shaped cells.
2. a type of soft tissue sarcoma whose cells are spindle-shaped and which is usually resistant to radiation therapy.

soft tissue sarcoma
Oncology A sarcoma that arises in muscle, fat, fibrous tissue, blood vessels, or other supporting tissues. See Sarcoma.
Soft tissue sarcoma staging
I A Tumor cells are morphologically similar to normal cells; tumor measures ≤ 5 cm
 B Ditto; tumor ≥ 5 cm
II A Tumor cells are mildly atypical; tumor measures ≤ 5 cm
 B Ditto; tumor ≥ 5 cm
III A Tumor cells are moderately or severely atypical/bizarre; tumor measures ≤ 5 cm
 B Ditto; tumor ≥ 5 cm
IV A Any cellular atypia; any sized tumor with lymph node involvement
 B Any cellular atypia; any sized tumor with metastasis  


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Byline: ANI Washington, September 23 (ANI): In what offers a new treatment option for people with soft-tissue sarcomas, experts have found that patients are 30 per cent more likely to be alive and cancer free almost three years after starting treatment if their tumours are heated at the time they received chemotherapy.
In the absence of any effective treatments for advanced soft-tissue sarcomas or refractory bone sarcomas that have spread, the orphan drug designations for AP23573 provided by the FDA should help us address this unmet medical need more effectively," said Harvey J.
At the 38th annual meeting of the American Society of Clinical Oncology in May 2002, the Sloan-Kettering team presented research in which they developed DNA expression profiles that can be used to accurately diagnose nine soft-tissue sarcoma subtypes, representing approximately 70% of these cancers.
 
 
 
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