NBTXR3 is being evaluated in: soft tissue sarcoma
(STS), head and neck cancers, prostate cancer, and liver cancers (primary and metastases).
Descriptive epidemiology of soft tissue sarcomas
in Vaud, Switzerland.
Approximately 12,000 patients in the United States and 29,000 patients in Europe are diagnosed with soft tissue sarcoma
1) Soft tissue sarcomas
, compared with carcinomas and other neoplasms are relatively rare and constitute fewer than 1% of all cancer.
Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas
of the extremities.
The present study includes 84 patients with retroperitoneal soft tissue sarcomas
hospitalized and operated in Universal Hospital "Queen Joanna" and Specialized Hospital for Active Treatment in Oncology--Sofia between 2001-2012.
In a previously reported randomized, controlled Phase 2 trial of palifosfamide plus doxorubicin versus doxorubicin alone in patients with unresectable or metastatic soft tissue sarcoma
(which trial was selected for the prestigious Best of ASCO designation in 2010) PFS showed a 3.
The CHMP's positive opinion is based on the results from Phase III study (Study 309)(1)comparing the efficacy and safety of Halaven versus dacarbazine in 452 patients (aged 18 or over) with locally advanced or recurrent and metastatic soft tissue sarcoma
(liposarcoma or leiomyosarcoma) who had disease progression following standard therapies which must have included an anthracycline and at least one other additional regimen.
Suggesting a clinical diagnosis as soft tissue sarcoma
1-3) A review of 20 years of experience in the Italian and German Soft Tissue Sarcoma
Cooperative Group identified 12 children with angiosarcoma.
Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma
in adults, comprising 20% to 40% of soft tissue sarcomas