mast cell stabilizers

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mast cell stabilizers

Prophylactic drugs used to treat allergic conjunctivitis, vernal conjunctivitis, giant pupillary conjunctivitis, superior limbic keratoconjunctivitis. They act by stabilizing the membranes of mast cells thus preventing the release of histamine. Common agents are sodium cromoglicate (cromolyn sodium), lodoxamide, nedocromil sodium, olopatadine hydrochloride and pemirolast potassium. See antihistamine; hypersensitivity.
References in periodicals archive ?
They can also sell or supply any P medicine, which includes one antibiotic within its P licence of use for bacterial conjunctivitis only, as well as products such as Otrivine Antistin and sodium cromoglicate, both for use with allergic conjunctivitis.
1 Opticrom Hayfever Eye Drops These soothing drops ease redness and irritation, and contain sodium cromoglicate which stops the body releasing the chemicals that cause itching (from pharmacies).
They get to work on itchy, puffy eyes in less than two minutes because they contain sodium cromoglicate, which relieves redness, watering and itchiness.
Eye drops containing drugs such as sodium cromoglicate and nedocromil sodium help prevent cells becoming sensitised and are used to reduce the eye symptoms of hayfever such as redness, itching and watering.
Most eye drops contain the compound sodium cromoglicate and well-known brands includeOpticromandOptrex.
a Cessation of lens wear and use of sodium cromoglicate eye drops until resolution
59,60,63) In the UK, 2% sodium cromoglicate is available to non-therapeutically trained optometrists in a pack size of 10ml and given the supporting literature it can be used to treat resistant CLGPC in normal contact lens practice.
Also Moorields pharmacy has introduced Catacrom, a preservative-free sodium cromoglicate, a mast cell stabiliser to treat hayfever compatible with contact lens wear
13-16) The logic of such a treatment might be questioned since sodium cromoglicate is not considered to have any constitutive anti-inflammatory activity; the removal of the stimulus to inflammation should help and better results might be obtained with other mast cell stabilisers/anti-eosinophil drugs such as lodoxamide or nedocromil sodium (both available to AS optometrists).
5% QDS for a few days) to generally quieten the eye, reduce lacrimation and photophobia as well as reduce further development of corneal infiltrates (27,30,35) As an inflammatory condition, some limbitis cases may respond to topical mast cell stabilizers (eg, regular use of sodium cromoglicate over one month).
For chronic and recurrent allergic conjunctivitis, part of an appropriate management approach is the use of 'mast cell stabilisers', (21) with several drugs marketed in the UK (eg, sodium cromoglicate, lodoxamide and nedocromil sodium).
786 Table 4: Other anti-inflammatory preparations Generic name Rxs (thousands) % Sodium Cromoglicate 1,129.