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Small Vessel Disease

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Lacunar Infarct
Any of multiple small cerebral infarcts in the corona radiata, internal capsule, striatum, thalamus, basis pontis, and/or cerebellum, occasionally preceded by transient symptoms, due to occlusion or stenosis of small penetrating branches of the middle and posterior cerebral and median branches of the basilar arteries; resolution of infarcts is characterised by residual 1–3-mm cavities or lacunae, characteristic of long-standing hypertension

small vessel disease
Neurology Cerebrovascular disease due to stenoses in small arteries of the brain. See Ministroke.


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2]-weighted MRI techniques are improving the ability to detect microbleeds, which are clear markers of hypertensive vasculopathy, cerebral amyloid angiopathy, and other underlying small vessel disease.
These diabetes complications are related to blood vessel diseases and are generally classified into small vessel disease, such as those involving the eyes, kidneys and nerves (microvascular disease), and large vessel disease involving the heart and blood vessels (macrovascular disease).
When microbleeds occur in certain brain areas, they may indicate a type of small vessel disease known as cerebral amyloid angiopathy, in which the accumulation of amyloid (a protein often related to Alzheimer's disease) causes degeneration of smooth muscle cells and increases the susceptibility of blood vessels to ruptures and hemorrhages.
 
 
 
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