ivermectin

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Related to Sklice: Ivermectin, Natroba, Ulesfia

i·ver·mec·tin

(ī'vĕr-mek'tin),
A semisynthetic macrolide antibiotic of the avermectin family of compounds, effective in the treatment of filariasis and many other parasites. The drug destroys Onchocerca microfilaria and Filaria bancrofti. Derived from the soil bacterium, Streptomyces avermitilis. Approved by the FDA for the treatment of scabies by topical administration. Widely used in veterinary medicine in a number of species for control of ectoparasites and endoparasites. Unusual sensitivity (increased toxicity, and sometimes death) in collie-type breeds is well documented.

ivermectin

(ī′vər-mĕk′tĕn)
n.
An anthelmintic and acaricide used to treat parasitic infections in livestock, to prevent heartworm infection in dogs, and to treat onchocerciasis, intestinal strongyloidiasis, and head lice in humans.

ivermectin

A drug used to kill MICROFILARIA in the treatment of ONCHOCERCIASIS and other microfilarial diseases. Ivermectin has also been used to treat severe SCABIES in elderly institutionalized people, but an unusually high death-rate in this group cast doubt on the safety of the application. The drug is on the WHO official list.

ivermectin

parasiticide; single-dose treatment for scabies

onchocerciasis 

A disease caused by infestation with the filarial worm (Onchocerca volvulus) spread by blackflies. It is common in tropical Africa and Central America, especially in areas near rivers. Large numbers of microfilariae are present on the skin and often enter the eye. The patient initially complains of itching, but blindness occurs as a result of chorioretinitis and optic neuritis. The disease is treated successfully with ivermectin. Syn. onchocercosis; river blindness.

ivermectin

an avermectin with broad activity against many helminths and arthropods. A broad-spectrum anthelmintic, acaricide and insecticide, used orally, subcutaneously and as a pour-on.
References in periodicals archive ?
It is not known if Sklice Lotion can harm your unborn baby.
It is not known if Sklice Lotion passes into your breast milk.
Important Safety Information for Sklice Lotion: To prevent accidental ingestion, adult supervision is required for pediatric application.
The most common side effects from Sklice Lotion include eye redness or soreness, eye irritation, dandruff, dry skin, and burning sensation of the skin.
who led the clinical trial programs for Sklice Lotion.
The FDA approval of Sklice Lotion was based on results of two randomized, double-blind phase 3 clinical trials that compared Sklice Lotion with a vehicle control (placebo) in 781 patients from the United States who were 6 months of age and older.
The FDA submission for Sklice Lotion included two identical multi-center, randomized, double-blind, vehicle-controlled studies conducted in subjects 6 months of age and older with head lice infestation.
No adverse events occurred at a rate greater than or equal to 1% in placebo-controlled trials using a single 10-minute treatment of Sklice Lotion in 379 patients ages 6 months and older.
The safety of Sklice Lotion has not been established in pediatric patients below the age of 6 months.
There are no adequate and well-controlled studies with Sklice Lotion in pregnant women.
In order to prevent ingestion, Sklice lotion should only be administered to pediatric patients under the direct supervision of an adult.