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abbr.

streptokinase

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abbreviation for streptokinase.

streptokinase [strep″to-ki´nās]

an enzyme produced by streptococci that catalyzes the conversion of plasminogen to plasmin. It is administered intravenously as a thrombolytic agent in the treatment of acute coronary arterial thrombosis, acute pulmonary embolism, deep venous thrombosis, and acute arterial thromboembolism or thrombosis. It is also used to clear obstructed arteriovenous cannulae. Detailed and skilled control is required in its use in order to avoid hemorrhage. It also can produce severe antigenic reactions upon readministration. See also anticoagulant.

streptokinase-streptodornase a mixture of enzymes elaborated by hemolytic streptococci; used as a proteolytic and fibrinolytic agent.

streptokinase.

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