MBTPS1

(redirected from Site-1 Protease)
Also found in: Acronyms.

MBTPS1

A gene on chromosome 16q24 that encodes a sterol-regulated subtilisin-like serine protease, which cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), releasing transcriptionally active SREBP fragments for translocation to the nucleus.
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