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sinusoid
(redirected from Sinusoids)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
sinusoid /si·nus·oid/ (si´nŭ-soid)
1. resembling a sinus.
2. a form of terminal blood channel consisting of a large, irregular anastomosing vessel having a lining of reticuloendothelium and found in the liver, heart, spleen, pancreas, and the adrenal, parathyroid, carotid, and hemolymph glands.
Enlarge picture
Sinusoids in a schematic view of a portion of a hepatic lobule.

si·nu·soid (sn-soid, -ny-)
n.
Any of the venous cavities through which blood passes in various glands and organs, such as the adrenal gland and the liver.
adj.
Resembling a sinus.

sinu·soidal (-soidl) adj.

sinusoid
[sī′nəsoid]
Etymology: L, sinus + Gk, eidos, form
an anastomosing blood vessel that is somewhat larger than a capillary and is lined with reticuloendothelial cells.

sinusoid [si´nŭ-soid]
1. resembling a sinus.
2. a form of terminal blood channel consisting of a large, irregular, anastomosing vessel, having a lining of reticuloendothelium but little or no adventitia. Sinusoids are found in the liver, adrenal glands, heart, parathyroid glands, carotid bodies, spleen, hemolymph glands, and pancreas.

sinusoid
1. resembling a sinus.
2. a form of terminal blood channel consisting of a large, irregular, anastomosing vessel, having a lining of reticuloendothelium but little or no adventitia. Sinusoids are found in the liver, adrenal glands, heart, parathyroid glands, carotid bodies, spleen, hemolymph glands and pancreas.


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This sign may stem from diverse pathophysiologic mechanisms, including dilated hepatic sinusoids (in heart failure), persistently high venous pressure leading to liver congestion (in chronic constrictive pericarditis), dysfunction and engorgement of hepatocytes (in hepatitis), fatty infiltration of parenchymal cells causing fibrous tissue (in cirrhosis), distention of liver cells with glycogen (in diabetes), and infiltration of amyloid (in amyloidosis).
The sinusoids become dilated and hepatocytes become necrotic when collagen accumulates in the sinusoids and venules.
The hepatic parenchyma is made of hepatocytes spread out as anastomotic cords arranged in two cellular layers surrounding the sinusoids (Figure 1B).
 
 
 
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