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A fast-acting vitamin K-antagonist anticoagulant. In patients with proximal vein thrombosis, it can be co-administered with full-dose heparin.


A fast-acting vitamin K-antagonist anticoagulant

acenocoumarol, acenocoumarin

a warfarin derivative used as an anticoagulant. Called also nicoumalone.
References in periodicals archive ?
Had the Company recorded Sintrom, Salagen and Estraderm on a gross basis, (which is explained below and better reflects in-market net sales) revenue for fiscal 2015 would have been $66.
L-carnitine does have drug interactions with warfarin, acenocoumarol/ Sintrom, and thyroid hormone.
The OSC concluded that the Company's acquisition of the intellectual property rights to market, distribute and sell the Sintrom product in certain European countries in September 2014 from Novartis triggered the requirement under National Instrument NI 51-102 "Continuous Disclosure Obligations" to file a business acquisition report including financial statements relating to the Sintrom product.
Sintrom (nicoumalone) is indicated for prevention and treatment of venous thrombosis (blood clots), the treatment of atrial fibrillation with embolization (irregular heart rhythms with obstruction), prevention and treatment of pulmonary embolism (obstruction of the pulmonary artery) and as an adjunct in the treatment of coronary occlusion (blockage of the coronary artery) and transient cerebral ischemic attacks (a mild form of stroke).