single-gene disorder

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Genetics A hereditary disorder caused by a mutant allele of a single gene–eg, cystic fibrosis, Duchenne muscular dystrophy, hemophilia, Huntington's disease, retinoblastoma, sickle cell disease; SGDs typically describe classic simple Mendelian patterns of inheritance–autosomal dominant, autosomal recessive, X-linked. See Gene, Mutation. Cf Polygenic disorder.

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Alpers' disease Andersen's disease chromosomal aberration Dejerine's disease Kienböck's disease Kinky Hair Disease Köhler's bone disease Krabbe's disease Kufs' disease Kyasanur Forest disease Lafora's disease			It is incredibly important that single-gene disorders like Duchenne muscular dystrophy are not left behind in the rush to treat more widespread diseases like cancer or diabetes. A rare ray of sunshine I will never, ever forget by The Mirror (London, England) As a result, it is estimated that 1 of every 1,800 individuals is affected, 1 of 21 is a carrier, and >400 individuals have the syndrome, making this syndrome the most frequent single-gene disorder on the island. Two Successful Vaginal Births after Cesarean Section in a Patient ... by Ronald D Beesley and Randal D Robinson and Theresa L Stewart / Military Medicine The Genetics of Alzheimer's Disease Diseases such as cystic fibrosis, muscular dystrophy, and Huntington's disease are single-gene disorders. Alzheimer's disease genetics by Pamphlet by: National Institute on Aging			single breath diffusing capacity single breath imaging single component insulin single donor transfusion single drug therapy single enterprise practice single essence single fiber electromyography single footling breech Single Limb Sport single nucleotide polymorphism single organ system examination single photon emission computed tomography single photon emission computer tomography single pulse cardioversion/defibrillation single room occupant single sweep scan single system ureterocele single unit transfusion single vessel disease single-blind study single-cell gel electrophoresis single-chain antigen-binding protein single-crystal sapphire single-foot single-gene disorder single-locus probe single-parent family single-payer system single-photon emission computed tomography SingleBAR singles bar singlet state singletary pea singleton Singulair singultus sinigrin sinister sinistr(o)- sinistr- sinistrad sinistral sinistrality sinistraural sinistro- sinistrocardia sinistrocerebral sinistrocular sinistrocularity sinistrogyration			single-family housing Single-Family Low Single-Family Owner-Occupied Rehabilitation Single-Family Rehabilitation Program Single-Family Residential Single-Feed Circular Microstrip Antenna Single-Feed element with Hybrid Feeding Single-Fiber Action Potential single-figure single-file Single-Fire/Dual Purpose Single-Flared Eyelet Single-Flux Quantum single-foot single-foot single-footed single-footed single-footer single-footer single-footing single-footing single-foots single-foots Single-Frame Majority-Decision single-framed roof Single-Frequency / Multi-View Single-Frequency Common View single-frequency duplex single-frequency simplex single-gene disorder single-gun color tube single-hand single-hand drilling single-handed Single-handed sailing single-handedly single-handedness single-hander single-handing single-hands single-heading flight single-hearted single-heartedly single-heartedness Single-Hit Poisson Model Single-Hole Pencil-Point Single-Hop Delay Single-Hop Gap Model Single-Hop Grooming single-hop transmission single-hub cartridge single-hub pipe Single-Hull Oil Tanker single-humped

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