SIX1

(redirected from Sine oculis homeobox homolog 1)

SIX1

A gene on chromosome 14q23.1 that encodes a homeobox protein similar to the Drosophila “sine oculis” gene product and thought to be involved in limb development.

Molecular pathology
SIX1 mutations are linked to autosomal dominant deafness type 23 and branchiootic syndrome type 3.
References in periodicals archive ?
We next matched genes in these three pathways with the 163 genes and identified 12 candidate genes: B-cell CLL/lymphoma 6 (BCL6), IL1[alpha] (ILIA), IL8, PTGS2, DTR, chemokine (C-X-C motif) ligand 3 (CXCL3), promyelocytic leukemia (PML), sine oculis homeobox homolog 1 (Drosophila) (SIX1), tumor necrosis factor (TNF), [alpha]-induced protein 3 (TNFAIP3), Zn finger and BTB domain containing 1 (ZBTB1), Zn finger protein 44 (KOX 7) (ZNF44), and Zn finger protein 450 (ZNF450).
63 SIX1 sine oculis homeobox homolog 1 (Drosophila) Hs.