silver sulfadiazine

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silver

 [sil´ver]
a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. (See Appendix 6.) It is used in medicine for its caustic, astringent, and antiseptic effects. It is also used in dentistry in alloys, in soldering, and as cones to obliterate the root canal.
silver nitrate colorless or white crystals, used as a caustic and local antiinfective; an important use is in prevention of ophthalmia neonatorum.
silver protein silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver sulfadiazine the silver derivative of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical antiinfective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
toughened silver nitrate a mixture of silver nitrate with hydrochloric acid, sodium chloride, or potassium nitrate, occurring as white crystalline masses molded into pencils or cones; a convenient means of applying silver nitrate locally.

sil·'ver sul·fa·di·a·zine

the silver derivative of sulfadiazine, used externally as a topical antibacterial agent in preventing and treating infections in burns.

silver sulfadiazine

a topical antibiotic.
indications It is prescribed to prevent or treat infection in second- and third-degree burns.
contraindications Known hypersensitivity to this drug, to silver, or to sulfonamides prohibits its use. It is not given in the last weeks of pregnancy or to newborn or premature infants.
adverse effects Among the most serious adverse effects are rash, fungal infection, neutropenia, and kernicterus.

sil·ver sul·fa·di·a·zine

(silvĕr sŭlfă-dīă-zēn)
Derivative of sulfadiazine, used externally as a topical antibacterial agent to prevent and treat infections in burns.

silver sulfadiazine

A drug used to treat infected leg ulcers, burns, skin graft donor sites and pressure sores (bedsores). The drug is on the WHO official list. A brand name is Flamazine.

sil·ver sul·fa·di·a·zine

(silvĕr sŭlfă-dīă-zēn)
Silver derivative of sulfadiazine, used externally as a topical antibacterial agent.

silver

1. a chemical element, atomic number 47, atomic weight 107.870, symbol Ag. See Table 6. It is used in medicine for its caustic, astringent and antiseptic effects. Experimental poisoning with silver salts causes myopathy.
2. a coat color in dogs, foxes.

silver amalgam
see amalgam.
silver collie syndrome
see canine cyclic hematopoiesis.
silver grass
aristidacontorta.
silver halide
any of the silver salts with halogens including bromine, chlorine, iodine used in photographic emulsion.
silver iodide
soluble silver salt used in cloud seeding but presents no toxicological risk to local grazing cattle.
silver-leaf ironbark
eucalyptusmelanophloia.
silver-leafed nightshade
solanumelaeagnifolium.
silver nitrate
colorless or white crystals, used as a caustic and local anti-infective.
silver nitrate (toughened)
a mixture of silver nitrate with hydrochloric acid, sodium chloride or potassium nitrate, occurring as white crystalline masses molded into pencils or cones, called caustic pencils; a convenient means of applying silver nitrate locally. Called also lunar caustic.
silver protein
silver made colloidal by the presence of, or combination with, protein; an active germicide with a local irritant and astringent effect.
silver stain
a method of demonstrating flagella on bacteria, or for visualizing very thin bacteria, such as leptospires.
silver sulfadiazine
the silver salt of sulfadiazine, having bactericidal activity against many gram-positive and gram-negative organisms, as well as being effective against yeasts; used as a topical anti-infective for the prevention and treatment of wound sepsis in patients with second and third degree burns.
silver weed

sulfadiazine

a rapidly absorbed and readily excreted sulfonamide antibacterial agent. Used commonly in triple-sulfa preparations. The sodium salt is used intravenously.

silver sulfadiazine
see silver sulfadiazine.
sodium sulfadiazine
an antibacterial compound used intravenously.
sulfadiazine-trimethoprim
a very popular combination of a potentiated sulfonamide because of its broad antibacterial spectrum and its small dose rate.
References in periodicals archive ?
From this technology Cypros has developed two initial products: Sildimac and Medimac.
Currently, Cypros has two approved products utilizing the Dimac system, Sildimac and Medimac.
It is expected that Medimac manufacturing will commence in the early summer and Sildimac manufacturing late in the year.
NASDAQ:CYPR), a Carlsbad-based marketer and developer of acute-care, hospital-based products, Tuesday announced the acquisition of two new proprietary acute-care products, Sildimac and Medimac from Enquay Inc.
Sildimac and Medimac are controlled-release forms of two widely used, topical wound-care drugs, which provide extended treatment periods with one drug application and are expected to greatly reduce treatment cost and increase patient compliance.
Sildimac contains silver sulfadiazine, the most widely used topical antimicrobial for the treatment of burns, and Medimac contains the active ingredients found in the widely used triple antibiotic Neosporin.
Medimac and Sildimac are incorporated into a patented topical drug delivery system (the "Dimac System"), which was also obtained in the acquisition.
The Sildimac product uses the Dimac System to deliver silver sulfadiazine topically in a controlled-release manner over a four-day period.
DIMAC serves as the storage and delivery system for the drug silver sulfadiazine to be used in the treatment of burns in burn centers and outpatient emergency rooms and has been given the trade name SILDIMAC Delivery System(TM).
United States Patent number 4,563,184 covering these products and a New Drug Application (NDA) approval for marketing of SILDIMAC has been granted by the Food and Drug Administration.
Bioplasty expects to begin manufacturing SILDIMAC in its new facility scheduled for completion sometime in mid-1992.