Leser-Trelat sign

(redirected from Sign of Leser-Trelat)

Le·ser-Tré·lat sign

(lā'zā trā'lah),
the sudden appearance and rapid increase in the number and size of seborrheic keratoses with pruritus; associated with internal malignancy.

Leser-Trélat sign

[lā′zər trālä′]
Etymology: Edmund Leser, German surgeon, 1828-1916; Ulysse Trélat, French surgeon, 1828-1890
a condition of malignant cells present in the skin, characterized by the sudden onset of multiple seborrheic keratoses, with pruritus or enlargement of preexisting keratosis in older adults. It is associated with adenocarcinoma of the stomach, breast cancer, and lung cancer.

Leser,

Edmund, German surgeon, 1828-1916.
Leser-Trélat sign - the sudden appearance and rapid increase in the number and size of seborrheic keratoses with pruritus, associated with internal malignancy.

Trélat,

Ulysse, French surgeon, 1828-1890.
Leser-Trélat sign - see under Leser
Trélat stools - stools streaked with blood, occurring in proctitis.
References in periodicals archive ?
Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trelat, and multiple acrochordons.
Internal malignancy associated with the sudden development of numerous seborrhoeic keratoses, in an eruptive fashion with or without pruritus, is generally accepted as the sign of Leser-Trelat.
The sign of Leser-Trelat with occurrence of multiple eruptive seborrheic keratoses is commonly associated with internal malignancies like gastrointestinal, breast carcinoma, lymphoma, leukemia or melanoma.
The sign of Leser-Trelat associated with carcinoma of the stomach.
Adenocarcinoma of the stomach with eruptive seborrheic keratoses: the sign of Leser-Trelat.
A case of the sign of Leser-Trelat associated with stomach cancer.
Oral acanthosis nigricans, tripe palms and sign of leser-trelat in a patient with gastric adenocarcinoma.
Sign of Leser-Trelat in newly diagnosed advanced gastric adenocarcinoma.
Seborrhoeic keratoses and carcinoma of the large bowel: three cases exhibiting the sign of Leser-Trelat.
A case of pancreatic cancer with the sign of Leser-Trelat.
Acanthosis nigricans and the sign of Leser-Trelat associated with adenocarcinoma of the gallbladder.
2 It may coexist with malignant acanthosis nigricans or sign of Leser-Trelat.