Sibutramine (redirected from Sibutramine hydrochloride)

sibutramine /si·bu·tra·mine/ (si-bu´trah-men?) an anorectic used as the hydrochloride salt in the management of obesity.

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si·bu·tra·mine (s-bytr-mn, -mn)

n.

A drug that suppresses appetite by inhibiting the reuptake of norepinephrine and serotonin, used in the management of obesity.

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Sibutramine

An appetite-suppressing drug that may increase the activity of norepinephrine and serotonin in the brain.

Mentioned in: Weight Loss Drugs

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sibutramine (sībū´trmēn),

n an FDA-approved prescription drug for weight loss containing a combination of serotonin and andronergics that has been shown to promote a feeling of fullness while apparently not influencing hunger; Meridia is an example.

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sibutramine Meridia^® Obesity A central, appetite-suppressing agent that blocks reuptake of serotonin and norepinephrine, and, to a lesser extent dopamine; it provides a sensation of fullness from less food, and ↑ metabolism Indications Obese Pts with an initial BMI of ≥ 30 kg/m2 or ≥ 27 kg/m2 with other factors–eg, HTN, DM, dyslipidemia Cons Sibutramine is a Schedule IV Controlled Substance Adverse effects Headache, dry mouth, anorexia, constipation Contraindications Concurrent MAOIs, other central appetite suppressants, anorexia nervosa. See Obesity.