Shwartzman phenomenon

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Shwartzman phenomenon [shwarts´man]

a local tissue reaction characterized by hemorrhagic necrosis due to an antigen-antibody reaction to certain bacterial substances. Its occurrence in humans is largely theoretical.

Shwartzman phenomenon, Shwartzman reaction, Shwartzman-Sanarelli reaction

a reaction to a second dose of bacterial endotoxin. It may be a local tissue reaction characterized by thrombosis, infarction and hemorrhagic necrosis, or generalized with disseminated intravascular coagulation and bilateral renal cortical necrosis.

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