alanine transaminase

(redirected from Serum glutamate pyruvate transaminase)
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alanine transaminase

 [al´ah-nēn trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate to form pyruvate and glutamate. Normally present in many tissues and body fluids, especially in the liver, it is released into the serum as a result of tissue injury; the serum concentration is increased particularly when there is acute damage to hepatic cells, as in viral or toxic hepatitis, infectious mononucleosis, and obstructive jaundice. Called also alanine aminotransferase and glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase (ALT),

(al'ă-nēn a-mē'nō-tranz'fer-ās),
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); one d-alanine transaminase effects the same reaction, but using d-alanine and d-glutamate. Serum concentration is increased in viral hepatitis and myocardial infarction.

alanine transaminase

/al·a·nine trans·am·i·nase/ (trans-am´ĭ-nās) an enzyme normally present in serum and body tissues, especially in the liver; it is released into the serum as a result of tissue injury, hence the concentration in the serum may be increased in patients with acute damage to hepatic cells.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase.

al·a·nine a·mi·no·trans·fer·ase

(ALT) (al'ă-nēn ă-mē'nō-trans'fĕr-ās)
An enzyme transferring amino groups from l-alanine to 2-ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction.
Synonym(s): glutamic-pyruvic transaminase, serum glutamic-pyruvic transaminase,
alanine transaminase.
References in periodicals archive ?
Parameters assayed were thiobarbituric acid reactive substance (TBARS), serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), reduced glutathione (GSH), ascorbic acid, tocopherol, super oxide dismutase and glutathione peroxidase in red blood cells (RBC) and in liver.
Serum glutamate oxaloacetate transaminase (SGOT) and Serum glutamate pyruvate transaminase (SGPT) enzymes are marker parameters of hepatic cell damage.
The heart damage induced by isoproterenol was indicated by elevated levels of the marker enzymes such as Creatine Kinase-isoenzyme (CK-MB), Lactate dehydrogenase (LDH), Serum Glutamate Oxaloacetic Transaminase (SGOT) and Serum Glutamate Pyruvate Transaminase (SGPT) in serum with increased lipid peroxide and reduced glutathione content in heart homogenates.

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