Interference caused by the contents of serum separator tubes
in the VITROS CRP assay.
Previous studies have suggested that serum separator tubes may have small analytical effects on many assays, but apart from the problem with therapeutic drugs, none of these effects was considered to be clinically significant (1, 3, 5-13).
In addition, the water-soluble silicone polymer coating the interior of serum separator tubes has been shown to interfere negatively with avidin-biotin binding in an IRMA for thyrotropin, prolactin, and human chorionic gonadotropin (25).
Serum separator tubes
contain polymeric gels with several constituents to adjust viscosity, density, and other physical properties.
Serum was collected into serum separator tubes
(Sarstedt) and centrifuged at 20008 for 10 min immediately after arriving in our laboratory.
Vacutainer[R] serum separator tubes
(SST[R] II) and plasma separator tubes (PST[R] II) manufactured by Becton Dickinson are widely used for blood collection.
Effect of serum separator tubes
on free and total phenytoin and carbamazepine serum concentrations.
Venous blood was collected from each of 10, nonfasting volunteers after antecubital venipuncture into 15 sterile (unopened) 5-mL Vacutainer [R] Serum Separator Tubes
with clot activator (SST; Becton Dickinson) and 15 sterile (unopened) 4.
3]) concentrations when blood specimens were collected in glass serum separator tubes
Two specimens collected in tiger top serum separator tubes
produced spuriously high aluminum values and were excluded from further analysis.
Briefly, venous blood was collected after phlebotomy simultaneously into serum separator tubes