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Sertoli cell |
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Sertoli cell any of the elongated cells in the tubules of the testes to which the spermatids become attached; they provide support, protection and, apparently, nutrition until the spermatids are transformed into mature spermatozoa. ovarian Sertoli cell tumor Sertoli-Leydig tumor of an atopic ovary in a bitch, commonly associated with cystic endometrial hyperplasia. testicular Sertoli cell tumor occurs most commonly in dogs, particularly in retained testicles. Production of estrogen may cause feminization in which the dog is attractive to other males with reduced libido, feminine distribution of body fat, symmetrical alopecia, atrophy of the penis, increased size of the mammary glands and prepuce, and prostatic enlargement. Rarely there is depression of bone marrow activity with anemia, thrombocytopenia and granulocytopenia. |
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