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As shown in Figure 2A, PDGFRA is highly expressed in the surrounding cells of the spermatic basement membrane (including Sertoli cells and spermatogonial stem cells) in 2-days testicular tissues.
Sertoli cell tumors are characterized by elongate cells with basal nuclei and moderate to abundant basophilic cytoplasm, arranged in a palisading manner around the central lumina of tubules.
Testicular tissue includes Leydig cells, which produce androgenic hormones, and Sertoli cells, which form the structure of the seminiferous tubules and support the production and maturation of the germ cells that develop into sperm.
Jacopo Sertoli, president, founder and CEO of Select Holding, said: "The Welcome Chinese programme was designed to bridge the gap between visitor expectations and the services the travel industry was providing, and I expect by welcoming more than twenty of Abu Dhabi's finest tourism products, the Emirate will appeal to a growing number of Chinese travellers.
All the cells of epithelium with a variety of spermatogonia, spermatocytes, spermatids and spermatozoa were observed in enveloped Sertoli cells (Figure 1A).
Neonatal exposure of BPA doses at 10 g/kg/day impairs fertility by protuberating Sertoli cell junctional protein (adhesion, gap, and tight junction) that leads to impaired spermatogenesis (Salian et al.
The advantage of ALTuCELL's patented non-invasive encapsulation technology is to infuse porcine-derived Sertoli cells without requiring immunosuppressant drugs.
Ezrin is an actin binding protein that regulates Sertoli cell and spermatid adhesion during spermatogenesis," Endocrinology 155(10); 3981-3995.
The development of the internal genitalia is dependent on the production, or lack of, of hormones from the foetal testis; both testosterone from the Leydig cells and anti-Mullerian hormone (AMH) from the embryonic Sertoli cells are needed.
It is well documented that normal functioning of the testis relies mainly on the action of follicle stimulating hormone (FSH) on the Sertoli cells and lutenizing hormone (LH) on the Leydig cells which subsequently acts on the semineferous tubules to maintain testis function.
Carbendazim, an inhibitor of microtubule synthesis, directly alters testicular function via germ cell depletion, alterations of Sertoli and Leydig cellular functions [18].
18) tarafindan yapilan bir calismada da AZFd bolgesinde delesyon oraninin %15,1 olarak bildirilmis ve bu olgularda maturasyon arresti ve sertoli cell only sendromu rapor edilmistir.