quetiapine(redirected from Seroquel XR)
Also found in: Dictionary.
quetiapine/que·ti·a·pine/ (kwĕ-ti´ah-pēn) a serotonin and dopamine antagonist used as the fumarate salt as an antipsychotic.
An antipsychotic drug, C21H25N3O2S, that acts as an antagonist of multiple neurotransmitters including serotonin and norepinephrine and is used in its fumarate form to treat schizophrenia and bipolar disorder.
indications It is used in the treatment of psychotic disorders.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Life-threatening effects are seizures, neuroleptic malignant syndrome, and tachycardia. Other adverse effects include extrapyramidal symptoms, pseudoparkinsonism, akathisia, dystonia, tardive dyskinesia, drowsiness, insomnia, agitation, anxiety, orthostatic hypotension, abdominal pain, dry mouth, rhinitis, rash, asthenia, back pain, fever, and ear pain. Common side effects include headache, dizziness, nausea, anorexia, and constipation.