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serotonin syndrome |
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Serotonin syndrome A group of symptoms caused by severely elevated serotonin levels in the body. Mentioned in: Antidepressant Drugs, SSRI serotonin syndrome Psychiatry A potentially life threatening condition caused by combined therapy with MAOIs and selective serotonin reuptake inhibitor–SSRI, antidepressants–Prozac, Zoloft, Paxil, Luvox,
Wellbutrin–bupropion, tryptophan or tricyclic antidepressants, which abruptly ↑ serotonin resulting in neuromuscular, autonomic, and behavioral changes due to ↑ CNS serotonin activity Clinical Confusion, diaphoresis, ataxia,
excitement, hyperthermia, hyperreflexia, myoclonus, hypotension, tremor Complications DIC, rhabdomyolisis, cardiovascular compromise Management D/C offending drug, support vital functions, dantrolene–muscle relaxant,
Periactin–cyproheptadine–antihistamine, serotonin antagonist. See MAOI, SSRI. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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