Semple vaccine

Sem·ple vac·cine

a modification of the original (Pasteur) rabies vaccine, formerly widely used in the U.S., prepared from rabbit nerve tissue, inactivated with phenol and administered in 14-21 daily injections; has variable potency and is associated with a high incidence of postvaccinal demyelination.


Sir David, English physician, 1856-1937.
Semple vaccine - a modification of the original rabies vaccine.
References in periodicals archive ?
Before the 1980s, nerve tissue-derived Semple vaccine was manufactured using the fixed RABV Beijing strain 3aG, which was isolated in 1931.