second messenger

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sec·ond mes·sen·ger

an intermediary molecule that is generated as a consequence of hormone-receptor interaction, for example, see adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, calcium, inositide.

second messenger

a chemical substance inside a cell that carries information farther along the signal pathway from the internal part of a membrane-spanning receptor embedded in the cell membrane. It may be in the form of an enzyme's product or ion fluxes. Ca2+, nitric oxide, and cAMP are common examples.
References in periodicals archive ?
One drug which we know directly affects the second messenger system is lithium, which directly affects activation of protein kinase C, which in turn activates protein synthesis of .
We are particularly interested in the signaling cascade that utilizes the phospholipase C b4 (PLCb4) second messenger system.
mediated second messenger system causes saliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glands.
An initial neurotransmitter will activate the fast ion channel receptor, while a second or third neurotransmitter will activate the second messenger system that modifies the effect of the initial transmitter.