Sclerosis

sclerosis /scle·ro·sis/ (-ro´sis) an induration or hardening, especially from inflammation and in diseases of the interstitial substance; applied chiefly to such hardening of the nervous system or to hardening of the blood vessels.

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amyotrophic lateral sclerosis  Lou Gehrig disease: progressive degeneration of the neurons that give rise to the corticospinal tract and of the motor cells of the brain stem and spinal cord, resulting in a deficit of upper and lower motor neurons; it usually has a fatal outcome within 2 to 3 years.

arterial sclerosis  arteriosclerosis.

arteriolar sclerosis  arteriolosclerosis.

diffuse cerebral sclerosis  the infantile form of metachromatic leukodystrophy.

disseminated sclerosis  multiple s.

familial centrolobar sclerosis  Pelizaeus-Merzbacher disease.

glomerular sclerosis  glomerulosclerosis.

hippocampal sclerosis  loss of neurons in the region of the hippocampus, with gliosis; sometimes seen in epilepsy.

lateral sclerosis  degeneration of the lateral columns of the spinal cord, leading to spastic paraplegia. See amyotrophic lateral sclerosis and primary lateral sclerosis

Mönckeberg's sclerosis  see under arteriosclerosis.

multiple sclerosis  (MS) demyelination occurring in patches throughout the white matter of the central nervous system, sometimes extending into the gray matter; symptoms of lesions of the white matter are weakness, incoordination, paresthesias, speech disturbances, and visual complaints.

primary lateral sclerosis  a form of motor neuron disease in which the degenerative process is limited to the corticospinal pathways.

progressive systemic sclerosis  systemic scleroderma.

tuberous sclerosis  an autosomal dominant disease characterized by hamartomas of the brain (tubers), retina, and viscera; mental retardation; seizures; and adenoma sebaceum.

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scle·ro·sis (skl-rss)

n. pl. scle·ro·ses (-sz)

1. The hardening of a tissue or part due to chronic inflammation.

2. A thickening or hardening of a body part or system especially from excessive formation of fibrous interstitial or glial tissue.

3. Any of various diseases characterized by thickening or hardening, such as arteriosclerosis.

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Sclerosis

The process by which an irritating material is placed in the pleural space in order to inflame the pleural membranes and cause them to stick together, eliminating the pleural space and recurrent effusions.

Mentioned in: Pleural Effusion, Scleroderma

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sclerosis (sklerō´sis),

n 1. a hardening of a tissue.
2. as applied to the jaws, sclerosis usually indicates an increased calcification centrally, with radiopacity.
3. as applied to dentin, the tracts of increased density in the dentin are referred to as areas of
dentinal sclerosis. It occurs beneath caries and with abfraction, abrasion, attrition, and erosion.

sclerosis, dentinal

n an occlusion of the dentinal tubules that inhibits outward fluid flow. It can occur naturally as root dentin ages but can also be caused by trauma, abrasion, or bacterial invasion. The sclerosing of the tubules produces translucent areas in the dentin.

sclerosis, multiple (MS),

n a remitting and relapsing disease of the central nervous system affecting principally the white matter. Manifestations include sensory and motor incoordination and paresthesias; often dementia, blindness, paraplegia, and death result.

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sclerosis

an induration or hardening, especially hardening of a part from inflammation and in disease of the interstitial substance. The term is used chiefly for such a hardening of the intestine in the dog, hardening of the nervous system due to hyperplasia of the connective tissue or for hardening of the blood vessels.

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arteriolar sclerosis

arteriolosclerosis.

nuclear sclerosis

increased density of the lens causing a gray-blue haze; seen as a normal feature of aging in dogs. This is often mistaken as cataract formation, but seldom is a cause of blindness.