Schick test

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Schick test

 [shik]
intracutaneous injection of diluted diphtheria toxin equal to one-fiftieth of the minimum lethal dose. Lack of immunity to diphtheria is indicated by redness and edema appearing at the injection site in 24 to 36 hours and lasting four to five days. This test has now largely been replaced by hemagglutination inhibition tests.

Schick test

(shik),
a test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 mL of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); those with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24-36 hours at the test site only and persisting for 4-5 days.
Synonym(s): Schick method

Schick test

(shĭk)
n.
A test to determine immunity to diphtheria by injection into the skin of dilute diphtheria toxin. Inflammation of the injected area indicates a lack of immunity.

Schick test

[shik]
Etymology: Bela Schick, Austrian-American physician, 1877-1967
a skin test formerly used to determine immunity to diphtheria in which dilute diphtheria toxin is injected intradermally. A positive reaction, indicating susceptibility, is marked by redness and swelling at the site of injection; a negative reaction, indicating immunity, is marked by absence of redness or swelling.

Schick test

An obsolete test once used to detect immunity to diphtheria toxin, based on response to subcutaneous heat-inactivated toxin.

Schick test

(shik test)
An assessment for susceptibility to Corynebacterium diphtheriae toxin. Schick test toxin is injected into the skin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness.

Schick test

A skin test of susceptibility to DIPHTHERIA. (Bela Schick, 1877–1967, Hungarian-born American paediatrician).

Schick,

Bela, Austrian pediatrician in U.S., 1877-1967.
Schick method - Synonym(s): Schick test
Schick sign
Schick test - for susceptibility to Corynebacterium diphtheriae toxin. Synonym(s): Schick method
Schick test toxin - Synonym(s): diagnostic diphtheria toxin

Schick test

(shik test)
An assessment for susceptibility to Corynebacterium diphtheriae toxin.

Schick test (shik),

n.pr a skin test used to determine immunity to diphtheria in which diphtheria toxin is injected intradermally. A positive reaction, indicating susceptibility, is marked by redness and swelling at the site of injection; a negative reaction, indicating immunity, is marked by absence of redness and swelling.