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saxitoxin

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
saxitoxin /saxi·tox·in/ (sak´sĭ-tok″sin) a powerful neurotoxin synthesized and secreted by certain dinoflagellates, which accumulates in the tissues of shellfish feeding on the dinoflagellates and may cause a severe toxic reaction in persons consuming contaminated shellfish.
sax·i·tox·in (sks-tksn)
n.
A potent neurotoxin produced by certain dinoflagellates that accumulates in shellfish feeding on these organisms and consequently causes food poisoning in humans who eat the shellfish.

saxitoxin
[sak′sitok′sin]
a powerful neurotoxin found in bivalve mollusks, including mussels, clams, and scallops. It is produced by certain species of dinoflagellates, which are consumed by the mollusks. Saxitoxin may cause a severe food intoxication in humans who eat the contaminated shellfish.

Saxitoxin
A potent paralyzing neurotoxin first isolated from the Alaskan clam—Saxidomus giganteus—which binds to the cell membrane’s Na+ channel, blocking depolarisation at the neuromuscular junction, and increasing permeability for Na+; the toxin is heat-stable, water-soluble and rapidly absorbed from the GI tract; as few as 6 contaminated clams may be fatal

saxitoxin [sak´sĭ-tok″sin]
a powerful heat-stable low molecular weight neurotoxin synthesized and secreted by certain dinoflagellates, such as species of Gonyaulax, which accumulates in the tissue of bivalve mollusks feeding on the dinoflagellates; it may cause a severe toxic reaction called shellfish poisoning in those who ingest contaminated mollusks.

saxitoxin
neurotoxic tetrahydropurine of the paralytic shellfish poisoning (PSP) toxin group from poisonous mussels, clams and plankton; a sodium channel blocker with the same mode of action as tetrodotoxin; originates in some toxic dinoflagellates and in some anabaena spp.


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Now, Kohane and colleagues reported that if saxitoxin is packaged within liposomes, it is able to block nerve transmission of pain without causing significant nerve or muscle damage.
Kohane and his colleagues have found that when saxitoxin is packaged within liposomes, it is able to block nerve transmission of pain without causing significant nerve or muscle damage.
 
 
 
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