Sandhoff's disease


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Sandhoff's disease

 [sand´hofz]
a variant of tay-sachs disease not restricted to particular ethnic groups and marked by a progressively more rapid course; it is due to a defect in the enzymes hexosaminidase A and B.

Sandhoff's disease

a variant of Tay-Sachs disease that includes defects in the enzymes hexosaminidase A and B. It is characterized by a progressively more rapid course and is found in the general population, not a restricted population as is Tay-Sachs disease. Also called gangliosidosis type II. See also Tay-Sachs disease.

Sandhoff's disease