STR


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Str.

abbreviation for Streptococcus.

STR

Abbreviation for:
scotopic threshold response
seven-transmembrane receptor
short tandem repeat
single-twitch response
soluble transferrin receptor
Specialty Registrar (StR), see there  
Structured Training Report, see there 
subtotal resection
superior temporal region
supratrigeminal region
systolic time ratio

Streptococcus

(strep?to-kok'us) [ strepto- + coccus],

Str

A genus of gram-positive, facultatively anaerobic cocci of the family Streptococcaceae, in which the cells tend to form chains or pairs. Many species are saprophytes, but others are virulent pathogens. They may be classified as alpha (a), beta (ß), and gamma (?) on the basis of their growth on blood agar plates and the hemolysis produced. Alpha-hemolytic streptococci produce partial hemolysis and create a greenish coloration around the colonies. Beta-hemolytic types completely hemolyze blood and form clear zones round colonies; those of the gamma type are nonhemolytic and do not change the color of the medium. Streptococci are also classified into several immunological groups (Lancefield groups) designated by the letters A through H, and K through O. Most human infections are caused by groups A, B, D, F, G, H, K, and O. Approximately 100 types of group A beta-hemolytic streptococci have been identified. See: rheumatic fever; scarlet fever

Streptococcus agalactiae

A group B ß-hemolytic species found in raw milk that is the leading cause of bacterial sepsis and meningitis in newborns and a major cause of endometritis and fever in postpartum women.

Infected infants develop early-onset symptoms in the first 5 days of life, including lethargy, jaundice, respiratory distress, shock, pneumonia, and anorexia. The fatality rate is 50% for very low birth weight neonates and 2% to 8% in term infants.

Infected postpartum women develop late-onset symptoms 7 days to several months after giving birth. Symptoms include sepsis, meningitis, seizures, and psychomotor retardation. Neonatal infection may be prevented by detecting colonization by these bacteria in pregnant women and by administering antibiotics prior to birth.

Synonym: Streptococcus, Group B

Streptococcus anginosus

A species that causes abscesses. It was formerly known as S. milleri.

Streptococcus bovis

The former name of a species now known as S. gallolyticus.

Streptococcus dysgalactiae subsp. equisimilis

A species that causes skin infections, such as erysipelas, as well as puerperal sepsis, osteomyelitis, pneumonia, bacteremia, and endocarditis.

Streptococcus equisimilis

The former name of a species now known as S. dysgalactiae subsp. equisimilis .

Streptococcus faecalis

The former name of Enterococcus faecalis.

Streptococcus gallolyticus

A species that causes bloodborne infections, esp. in patients with diseases of the large bowel, e.g. colon cancer.

Streptococcus, Group B

Streptococcus agalactiae.

Streptococcus iniae

A species pathogenic to fish that may cause cellulitis in people who handle affected fish and have skin abrasions.

Streptococcus mutans

A species that has been implicated in initiation of dental caries and bacterial endocarditis.

Streptococcus pneumoniae

A species that occurs in pairs with capsules and may be part of the transient flora of the upper respiratory tract. Based on capsular chemistry, more than 80 serological types have been identified. It is the causative agent of certain types of pneumonia, esp. lobar pneumonia, and is associated with other infectious diseases such as meningitis, conjunctivitis, endocarditis, periodontitis, septic arthritis, osteomyelitis, otitis media, septicemia, spontaneous bacterial peritonitis, and, rarely, urinary tract infections. About 40,000 people die of pneumococcal disease each year in the U.S., more than from any other vaccine-preventable illness.
Synonym: pneumococcus

Streptococcus pyogenes

Any of the group A ß-hemolytic streptococci causing suppurative infections. These streptococci are the causative agents of scarlet fever, erysipelas, bacterial pharyngitis, puerperal sepsis, and necrotizing fasciitis.

STR

abbrev. SHORT TANDEM REPEAT.
References in periodicals archive ?
Bruce Wiechert Custom Homes Inc, 838 Mountaingate Dr; STR - New single family residence; $402,132.
Mike Blankenship Corporation, 1146 S 40th CT; STR - Single family residence; $195,489.
STR is an innovative cancer therapeutic that delivers radiation directly to cancer cells in the bone and bone marrow, thereby minimizing exposure of normal tissues to radiation.
The Company's product pipeline includes STR and NX 473, a next-generation platinum therapy that the Company plans to evaluate in the treatment of patients with advanced lung and colorectal cancers.
The Company is currently conducting a multi-center, randomized, controlled Phase III pivotal trial designed to evaluate the safety and efficacy of STR in patients with primary refractory multiple myeloma.
Jerry McMahon, PhD, Chairman and CEO of NeoRx, commented, "Filing this IND is in keeping with our strategy to broaden the use of STR to treat patients with bone metastases from other major types of cancer.
David Maloney of the Fred Hutchinson Cancer Research Center, Vincent Rajkumar of the Mayo Clinic, and Paul Richardson of the Dana-Farber Cancer Institute, who will share highlights from the ASCO 2004 Annual Meeting, including a discussion of the STR clinical data presented by Dr.
The phase III pivotal trial is a multi-center, randomized, controlled study, designed to evaluate the safety and efficacy of STR in patients with primary refractory multiple myeloma.
This agreement with MURR marks the continuation of a long and successful relationship between our two organizations, and provides NeoRx a reliable source of holmium for production of STR for the phase III registration trial," said Jack L.
NeoRx is a cancer therapeutics development company with a lead product candidate, STR, entering a phase III clinical study in multiple myeloma, a cancer of the bone marrow.
NeoRx is developing STR for use with high-dose chemotherapy and stem cell transplantation to treat multiple myeloma and other cancers that arise in or spread to the bone marrow.