STK39

STK39

A gene on chromosome 2q24.3 that encodes a serine/threonine protein kinase thought to mediate stress-activated signals. It is primarily expressed in the brain and pancreas.
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Whole-genome association study identifies STK39 as a hypertension susceptibility gene.
According to the results of a study being published online in the Proceedings of the National Academy of Sciences (PNAS), the STK39 gene is the first hypertension susceptibility gene to be uncovered through a new technique called a genome-wide association study and confirmed by data from several independent studies.
The STK39 gene is only one important piece of the puzzle," she says.
The University of Maryland researchers identified the link between the STK39 gene and blood pressure by analyzing the DNA of 542 members of the Old Order Amish community in Lancaster County, Pennsylvania, scanning approximately 100,000 genetic markers across the entire genome for variants known as single nucleotide polymorphisms, or SNPs, associated with systolic and diastolic blood pressure.