SPINK


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SPINK

Serine protease inhibitors, Kazal type. Any of a family of genes (5 are confirmed: SPINK1, -2, -4, -5, -6; 3 more SPINKs are postulated), which encode trypsin ihibitors in various tissues. As an example, SPINK1 on chromosome 5q32 encodes a trypsin inhibitor, secreted by pancreatic acini which appears to prevent trypsin-catalysed activation of zymogens in the pancreas.
 
Abnormal
SPINK1 mutations are linked to hereditary pancreatitis and tropical calcific pancreatitis.
References in periodicals archive ?
Prior to joining First Northern in 2015, Spink spent seven years with KPMG, LLP where he gained significant audit expertise in the banking and finance industries, and five years with Rabobank where his last position was Senior Vice President/Chief Accounting Officer.
Spink, 69, served as Tory MP for Castle Point in Essex for five years before defecting to UKIP in 2008.
This recent sale exceeds the previous record of just under HK$2 million, also held by a cask of Macallan whisky sold at Spink auction house China, set on Friday 4 July 2014.
And Spink, who remains a follower of the claret and blues.
We are pursuing the local production route because it works" says Spink.
Spink, of Batley Street, Moldgreen, admitted charges of racially-aggravated assault, causing a danger to road users and possession of cannabis.
Lifetime Achievement Award winner Nigel Spink with Willy Thorne and Peter Whitehead (Baker Tilly).
Despite his prolific stint at the club, Spink has largely remained an unsung hero.
European Cup winner Spink was Gordon's keeper coach at Sunderland following the former Hearts man's British record PS9million move in 2007.
Scotland's best known fish smoker and curer, Arbroath based RR Spink, is achieving huge success with its super premium selection of hot smoked salmon and trout products.
Arbroath based smoked fish specialist RR Spink is celebrating the securing of two major contracts which will between them be worth [pounds sterling]4.
Marks & Spencer smoked salmon supplier RR Spink has secured new supply deals for two new added-value fish ranges.