SPINK


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SPINK

Serine protease inhibitors, Kazal type. Any of a family of genes (5 are confirmed: SPINK1, -2, -4, -5, -6; 3 more SPINKs are postulated), which encode trypsin ihibitors in various tissues. As an example, SPINK1 on chromosome 5q32 encodes a trypsin inhibitor, secreted by pancreatic acini which appears to prevent trypsin-catalysed activation of zymogens in the pancreas.
 
Abnormal
SPINK1 mutations are linked to hereditary pancreatitis and tropical calcific pancreatitis.
References in periodicals archive ?
Villa have enjoyed some great goalkeepers over the years with Spink and Jimmy Rimmer springing immediately to mind.
He was arrested and Spink started remonstrating with the officers detaining him.
Lifetime Achievement Award winner Nigel Spink with Willy Thorne and Peter Whitehead (Baker Tilly).
Despite his prolific stint at the club, Spink has largely remained an unsung hero.
Spink is the world's leading auctioneer of stamps, coins, banknotes, medals, bonds & shares, autographs and books.
European Cup winner Spink was Gordon's keeper coach at Sunderland following the former Hearts man's British record PS9million move in 2007.
31, 2012 /PRNewswire/ --Johnson Controls, a global leader in automotive seating, overhead systems, door and instrument panels, and interior electronics, announced that it has formed a development relationship with luxury mattress manufacturer Harrison Spinks to integrate pocketed coil spring mattress technology into an automotive seat concept called ComfortThin.
To manufacture the products Spinks has spent [pounds sterling]200,000 on new processing equipment, including an additional vacuum skin packing machine from equipment supplier VC999.
5m for Spink, part of the Dawnfresh Seafoods group.
THE coin and medal specialist auctioneers Spink sold the VC and its accompanying medals in their Orders, Decorations, Campaign Medals and Militaria auction last week.
DARREN SPINK is targeting a World Cup place - even though he couldn't get a game for Montrose last season.
Jansen, Spink, and Saracevic (2000) report that Web queries were short and most users did not enter many queries per search.