PCSK7

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PCSK7

A gene on chromosome 11q23-q24 that encodes a ubiquitous endoprotease of the peptidase S8 family involved in the constitutive secretory pathway that cleaves the RXXX(K/R)R consensus motif. It is localised intracellularly to the trans Golgi network and is expressed in the spleen, thymus, prostate, testes, ovaries, small intestine, colon and peripheral leukocytes.