SPAG11B

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SPAG11B

A gene on chromosome 8p23.1 that encodes sperm-associated antigen 11B, an androgen-dependent, epididymis-specific secretory protein of unknown function.
References in periodicals archive ?
Amino acid sequence analysis showed that Bin1b corresponds to SPAG11 variant E.
The amplification of the predicted SPAG11 variant C transcript by RTPCR has been also reported in the rat and mouse epididymis.
64) RTPCR examination showed that hBD-4, hBD-5, hBD6, and SPAG11 variant D were expressed predominantly in the human epididymis (Table 1).
SPAG11 variant E expression was also most prominent in the caput region, but a comparable level of expression was detected in the corpus region.
In humans, the former group includes SPAG11 variant D, hBD-4, hBD-5, and hBD-6, and the latter group includes hBD-1, hBD-2, and hBD-3.
Immunostaining for SPAG11 family proteins indicated the binding of SPAG11 to the sperm head, suggesting a possible role in sperm maturation.