SP1


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SP1

Abbreviation for stimulatory protein 1.

SP1

A gene on chromosome 12q13.1 that encodes a transcription factor  which up- or downregulates transcription in response to physiological and pathological stimuli. SP1 binds with high affinity to GC-rich motifs and regulates expression of an array of genes involved in various cell processes, including growth, differentiation, immune responses and apoptosis; it may have a role in modulating cell responses to DNA damage and is implicated in chromatin remodelling. SP1 is highly regulated by post-translational modification—e.g., phosphorylation, sumoylation, proteolytic cleavage, glycosylation and acetylation.
References in periodicals archive ?
Pairwise comparisons between antibodies are summarized in Table 2 and include 14 cores with significant differences in interpretations between SP1 and 1D5, 12 between SP1 and 6F11, and 4 between 1D5 and 6F11.
The same principle was applied to construct a modified SP1 variant, capable of forming reversible and non-covalent molecular associations with carbon-based nanoparticles (CNPs), such as carbon nanotubes (CNT), carbon black (CB) and graphene nanoparticles (the SP1/CNP complex), forming a stable nano-metric CNP dispersion binding to polymer fibers.
SP1 will be released gradually over the coming weeks to all customers on the RTM version of Windows 7.
8220;Since Exchange 2010 SP1 in hosting mode doesn't allow the usage of the Exchange Management Console (EMC), therefore HC control panel becomes the natural choice of hosted service providers to provision organizations and mailboxes in Exchange 2010 using a special '/hosting' switch in Hosting Mode.
Designed to address customer needs for reliable, high performing and secure computing across the enterprise, SUSE Linux Enterprise 11 SP1 contains major upgrades to the following products:
SP1 in pregnancies with Down syndrome in the first trimester of pregnancy.
Additional enhancements in isCOBOL APS 2008 SP1 include:
In addition, SP1 includes some additional security safeguards and drivers that support an even wider array of hardware.
En este modulo Informaremos como se utiliza Vista y todo lo que se puede hacer con este sistema; con SP1 se empiezan a cubrir esa faltas que tenia el software cuando se lanzo; explico.
SP1 addresses feedback from Microsoft's customers and delivers improvements in security, reliability and performance.
Trend Micro has worked closely with Microsoft to ensure our security products are optimised for Windows Vista SP1," said Carol Carpenter, vice president of consumer marketing and product management for Trend Micro.
Trend Micro has worked closely with Microsoft to ensure our security products are optimized for Windows Vista SP1," said Carol Carpenter, vice president of consumer marketing and product management for Trend Micro.