SOCS5

SOCS5

A gene on chromosome 2p21 that encodes a protein of the suppressor of cytokine-signalling (SOCS)—i.e., STAT-induced STAT inhibitor (SSI)—protein family, which are cytokine-inducible negative regulators of cytokine signalling. SOCS5’s specific function is unknown.
References in periodicals archive ?
SOCS5, reported in this paper, is one of the several new "cooperating" cancer genes to be identified through this innovative approach.
Already, there are indications that levels of SOCS5 expression are reduced in breast cancer, and patients with low levels of SOCS5 have poor prognosis.
The IMCB team is preparing to explore the use of SOCS5 as a biomarker in diagnosis for cancer.