ABCC5

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ABCC5

A gene on chromosome 3q27 that encodes a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes, many of which are involved in multidrug resistance. ABCC5 exports its substrate, cyclic nucleotides, contributing to the degradation of phosphodiesterases, and may be an elimination pathway for cyclic nucleotides. ABCC5 is linked to resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, in patients with acute lymphocytic leukaemia, and resistance to antiretroviral nucleoside analogues (e.g., 9-(2-phosphonylmethoxyethyl)adenine) in HIV-infected patients.
References in periodicals archive ?
SMRP provides value for individual practitioners and companies who practice and sustain maintenance, reliability and physical asset management best practices.
Neither a storage temperature of 37 [degrees]C nor hemolysis resulting from storing unprocessed blood samples over extended periods of time (at 2-8 [degrees]C and 37 [degrees]C had a significant effect on measured SMRP.
Thirteen communities were awarded $1,239,422 in SMRP grants for the purchase of wheeled carts for the implementation or expansion of curbside single-stream recycling.
For more information on the SMRP Approved Provider Program, visit our website.
Previously sold as a stand-alone product, the metrics are now a benefit of SMRP membership and still available to purchase for non-members at $50 for one or $395 for all 67.
For years, we've believed SMRP played a role in the classification of the disease, but there was no accurate way to confirm it.
This is a milestone for SMRP, and we are excited to recognize colleagues in the M&R industry who stand out from the crowd - even among a distinguished group like CMRP holders," said SMRP Chair Shon Isenhour, CMRP.
Pricing for The Discovery WineStation starts at $5,299 SMRP and is available through authorized Dacor retailers nationwide.
x transponders supporting loopback functionality via SMRP, including Tollgrade Cheetah(R) transponders and end-of-line probes which were recently awarded Minacom Certified VoIP Test Integration.
About SMRP The Society for Maintenance and Reliability Professionals (SMRP) is a not-for-profit professional society formed by practitioners to serve leaders and advance Reliability and Physical Asset Management.
With this announced interoperability, operators can now use Minacom's PowerProbe(R) service level test probes running the Real-time Transport Protocol (RTP) Streamer test agent to perform loopback tests to Electroline transponders supporting the SMRP protocol.