SMN2

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SMN2

A gene on chromosome 5q13.2 that encodes a survival motor neuron protein which is a component of an import snRNP complex composed of KPNB1, RNUT1 and ZNF259. It interacts with OSTF1, LSM10 and LSM11.

Molecular pathology
Defects of SMN1 cause spinal muscular atrophy types 1–4. The severity of disease is mainly determined by the copy number of SMN2, a copy gene which predominantly produces exon 7-skipped transcripts and only low amount of full-length transcripts that encode for a protein identical to SMN1.
References in periodicals archive ?
In addition to the latest SMNC accomplishments, last week Mario Quenneville, President and CEO of SMNC received notification from a large Canadian retail chain store of their interest in selling all of their Superwipes products lines.
Petersburg Times interviewed me today regarding SMNC sponsorship for Joe Nolfo's Great American Motorcycle Ride around the United States to raise awareness for the Center for People with disabilities.
P & D Premiere Imports and SMNC have cleared the largest hurdle for entry into the Canadian marketplace," said Mario Quenneville, President and CEO of SMNC.
com, and MyGirl in this nationwide event," said Mario Quenneville, President and CEO of SMNC.
P & D Premiere Imports has the right to import into Canada the following SMNC products:
We will work vigorously with the SMNC team on an intensive program to locate distributors and partners in mainland China.
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SMNC expects these service improvements will likely impact the liquidity of its common stock.
SMNC will manufacture and sell its products with the full assurance that the Chapter 11 Proceeding had no merit, and it is over.
Tzu-Yin Chiu, Chief Executive Officer of SMIC and Chairman of SMNC, "LEED certification identifies SMNC Beijing 12-inch FAB Project as a showcase example of sustainable design and demonstrates your leadership in transforming the building industry.
Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number.
These nine orders submit to the authority of the SMNC, the members of which are indirectly elected by monks.