MYH11

(redirected from SMMHC)
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MYH11

A gene on chromosome 16p13.11 that encodes a heavy chain of myosin and is thus involved in cytokinesis, cell shape and specialised functions—e.g., secretion and capping.
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References in periodicals archive ?
Markers SMA (Figure 4), MSA, calponin, p63 (Figures 3, C and 5), maspin, p75, and SMMHC (Figure 2, B) are probably largely comparable in their sensitivities for MECs for scenarios in which the question is invasive carcinoma versus an entirely benign process, with the important caveat that sclerosing lesions of the breast may show patchy or no staining in a significant subset.
41) Calponin and SMMHC are expressed in collagenous spherulosis but not in adenoid cystic carcinoma.
Markers that most effectively combine sensitivity, specificity, and ease of interpretation include SMMHCs, calponin, p75, p63, P-cadherin, basal CKs, maspin, and CD10.