SHH

(redirected from SMMCI)
Also found in: Acronyms.

SHH

A gene on chromosome 7q36 that encodes a protein central in early embryonic patterning and the key inductive signal in patterning of the anterior-posterior limb axis, the ventral somites and the ventral neural tube.

Molecular pathology
Defects in SHH or in its signalling pathway cause holoprosencephaly, VACTERL syndrome; mutation upstream of SHH disrupts limb patterning and can result in preaxial polydactyly.
References in periodicals archive ?
In its proposed rehabilitation plan, SMMCI wanted BPI Savings Bank to: (a) defer foreclosing on the mortgage constituted to secure the loan extended to SMMCI; and (b) agree to a moratorium of at least two years before SMMCI would start servicing its loan obligation to the bank.
The SC said that while SMMCI had indeed commenced business by opening a credit line with BPI Family Bank to finance the construction of the new hospital building, it neither formally operated nor earned any income since its incorporation.
The failure of SMMCI to comply with this requirement prevent[ed] the Court from ascertaining if the petitioning debtor's creditors can recover by way of the present value of payments projected in the plan