SIX5

SIX5

A gene on chromosome 19q13.32 that encodes a homeodomain-containing transcription factor which regulates organogenesis.

Molecular pathology
SIX5 mutations are linked to branchiootorenal syndrome type 2.
References in periodicals archive ?
Alteracion de la expresion de DMPK y otros genes vecinos: La expansion de repeticiones CTG interfiere con la configuracion local de la cromatina, lo cual afecta la expresion de DMPK y otros genes vecinos como: DMAHP (dystrophia myotonica associated home domain protein)/ SIX5, DMWD (dystrophia myotonica containing WD) y MBNL1 (muscle blind protein) (12, 13).
Effect of triplet repeat expansion on chromatin structure and expression of DMPK and neighboring genes, SIX5 and DMWD, in myotonic dystrophy.