SHROOM3

SHROOM3

A gene on chromosome 4q21.1 that encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins, which may be involved in regulating cell shape. A homologue in mice is required for proper neurulation.
References in periodicals archive ?
Out of more than 2,500,000 genetic variants that were evaluated for each study participant, only three genes, UMOD, SHROOM3, and STC1 were found to be novel risk genes for reduced kidney function and chronic kidney disease.