SHH


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SHH

A gene on chromosome 7q36 that encodes a protein central in early embryonic patterning and the key inductive signal in patterning of the anterior-posterior limb axis, the ventral somites and the ventral neural tube.

Molecular pathology
Defects in SHH or in its signalling pathway cause holoprosencephaly, VACTERL syndrome; mutation upstream of SHH disrupts limb patterning and can result in preaxial polydactyly.
References in periodicals archive ?
In response, the PCC has again indicated that Viable must deal with the existing leaseholder, though the pressure group says the council has various levers available to force SHH to relinquish the lease.
Note also that within each pair, one game has only positive payoffs--like our SHH game--and the other had all negative payoffs except when both players choose the risky action--like our SHL game.
Se hizo un analisis de alelos, genotipos y haplotipos para determinar la asociacion de Shh y la FLPNS utilizando los test de desequilibrio de ligamiento (del ingles transmission-disequilibrium Test TDT), odd ratio y prueba de razon de verosimilitud.
A strip of Shh DNA (this, of course, is an abbreviated version of the true gene, containing only a single exon; see Appendix 1)
Mike, originally from Warrington, is working on Shh.
In the palate, these processes are regulated by TGF[beta]-3, but in the face this growth factor is not present in maxilar and nasal shelves and in lip formation would act other factors, such as Shh and BMP that have been shown to be involved in avian lip confluence.
Teachers usually adopted disciplinary methods that do not disrupt the flow of instruction such as shh, shh, shh, stop, ignoring, and repeating directions.
On the left side, the Shh protein spurs cNR-1 protein synthesis, while on the right side, a molecule called activin suppresses synthesis of Shh and stimulates production of cAct-RIIa.
SHH operates as one entity on two campuses and represents a significant portion of total revenues to the system, while also enjoying consistently positive operating margins.
It is known that axons follow the Shh signal during their development," explained Dr.
SHH, a double act from Buenos Aires have managed to make a 2010 electro equivalent.