SHC3

(redirected from SHC (Src homology 2 domain containing) transforming protein 3)

SHC3

A gene on chromosome 9q22.1 that encodes a signalling adapter protein involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. It is highly expressed in the brain, especially in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala.