GPC3

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GPC3

A gene on chromosome Xq26.1 that encodes glypican 3, a cell surface proteoglycan with heparan sulfate that inhibits the dipeptidyl peptidase activity of DPP4. It may be involved in modulating growth of mesodermal tissues, in IGF2-receptor interactions, and in cellular growth and tumourigenesis.

Molecular Pathology
Defects in GPC3 cause Simpson-Golabi-Behmel syndrome.
References in periodicals archive ?
Formed in March last year, SGBS aims to promote golf among youngsters in Saudi Arabia, support charity projects and build business links through golf.
As the year drew to a close, SGBS organized a Thursday afternoon stroke play tournament that attracted 40 players.
SGBS aims to create a link between Saudi businessmen and the expatriate community, according to Masoud adding they hope to attract more Saudis to take up the game of golf and that it is easier for them to start since they now have a community to join.
As well as promoting awareness and development of the sport SGBS is keen to play its part in the enforcement of golf rules and etiquette, Masoud said.
Along with Masoud two other officials namely Fahad Almansour, captain, and Fady Le Jreij, media and PR manager, attended the SGBS inaugural tournament.
According to Almansour SGBS was formed only last month.
The formation of SGBS is a key step in STS and SPP joining forces to deliver enhanced customer support globally.
Susumu Kaminaga, President of SPP and Chairman of STS added, "The formation of SGBS is a demonstration of our commitment to ensuring our customers receive an excellent experience when dealing with both STS and SPP.