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SERM

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
SERM
abbr.
selective estrogen receptor modulator

SERM,
modulator [mod´u-la″ter]
a specific inductor or agent that brings out characteristics peculiar to a definite region.
selective estrogen receptor modulator (SERM) an agent that activates some estrogen receptors but not others, thereby having estrogenlike effects on target tissues (such as bone) without affecting other tissues that have estrogen receptors.

SERM


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The team found that PCNA was increased when they stimulated cells with estrogen and decreased when they added a SERM, indicating that the SERM blocked cell growth.
Other currently available SERMs do not have an effect on vaginal tissue and may induce hot flashes.
As a future strategy, the concept of using tamoxifen or a SERM premenopausally, followed by an aromatase inhibitor postmenopausally, may be an optimal strategy for testing in trials," Dr.
 
 
 
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