ATP2A3

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ATP2A3

A gene on chromosome 17p13.3 that encodes a SERCA Ca2+-ATPase, an intracellular pump located in the sarcoplasmic or endoplasmic reticula of muscle cells, which catalyses the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscle contraction and relaxation.
References in periodicals archive ?
Three different SERCA genes were identified-SERCA1, SERCA2, and SERCA3.
The SERCA3 isoforms are differently co-expressed in a variety of cells and tissues including muscle and non-muscle tissues (17).
It interacts with SERCA1a, SERCA2a and SERCA2b but not SERCA3.