SENP1

SENP1

A gene on chromosome 12q13.1 that encodes sentrin-specific peptidase 1, which has two key roles:
(1) Processing of full-length SUMO1, SUMO2 and SUMO3 to mature forms; and
(2) Deconjugating SUMO1, SUMO2 and SUMO3 from targeted proteins.

It is highly expressed in the testes.
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References in periodicals archive ?
They identified two genes, ANP32D and SENP1, with significantly increased expression in the CMS individuals when compared to the non-CMS individuals, and hypothesized that down-regulating these genes could be beneficial in coping with hypoxia.