Currarino syndrome

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Currarino syndrome

An autosomal dominant condition (OMIM:176450) characterised by sacral agenesis, a presacral mass and anorectal malformation, variably accompanied by anterior meningocele or a presacral teratoma.

Molecular pathology
Defects in MNX1/HLXB9, which encodes a nuclear transcription factor involved in pancreas development and function, cause Currarino syndrome.

Currarino,

Guido, Italian-born U.S. radiologist, 1920–. U.S. radiologist born in Italy, 1920–.
Currarino triad - complex of anococcygeal congenital anomalies. Synonym(s): Currarino syndrome
Currarino-Silverman syndrome - growth abnormality of the sternum. Synonym(s): Silverman syndrome
Currarino syndrome - Synonym(s): Currarino triad